Multiple alignment of structures using center of proteins
نویسندگان
چکیده
Multiple structure alignment (MStA) is a fundamental tool for correlating the structural similarity of proteins with their functional similarity. A number algorithms are extant, MUSTANG, POSA, M...
منابع مشابه
Multiple Alignment of Structures Using Center Of ProTeins
Protein structure comparison has long been under investigation by computational biologists in hopes for finding a better but not necessarily faster alternative to the more familiar multiple sequence alignment problem. The multiple alignment problem is more challenging than pairwise alignment even for sequences, and we resort to heuristics to find as best an approximation as possible, in polynom...
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Most approaches for protein structure alignment start from a search for similar fragments since this local similarity is necessary to the alignment even though is insufficient. In contrary to the sequence alignment, any insignificant trial alignment for structures can be detected by structure superposition and then excluded. It is then practicable to select from locally similar fragments those ...
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ژورنال
عنوان ژورنال: International Journal of Bioinformatics Research and Applications
سال: 2021
ISSN: ['1744-5485', '1744-5493']
DOI: https://doi.org/10.1504/ijbra.2021.10037181